Herpes zoster
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Herpes zoster nu nyababkeun bisul dina beuheung jeung taktak
relevance score : -100.0%
ReferencesShingles, disababkeun ku réaktivasi virus varicella zoster anu tanggung jawab kana cacar, mangaruhan kira-kira 1 juta jalma unggal taun di Amérika Serikat, kalayan résiko maot 30 %. Jalma anu boga sistem imun lemah sacara signifikan leuwih rentan ngembangkeun shingles, kalayan gejala biasana dimimitian ku rasa lemes, nyeri sirah, jeung mual hampang, dituturkeun ku sensasi kulit anu teu biasa sababaraha dinten saméméh munculna ruam. Baruk ieu, biasana muncul dina wewengkon husus awak, maju ti lepuh jelas ka lesi keropos salila leuwih ti saminggu nepi ka sapuluh poé. Pangobatan gancang kalayan antiviral (acyclovir, valacyclovir, atawa famciclovir) dina 72 jam sanggeus munculna ruam penting pisan. Neuralgia postherpetic, komplikasi umum anu dicirikeun ku nyeri berkepanjangan di wewengkon nu katépaan, mangaruhan kira-kira hiji dina lima penderita sarta merlukeun manajemén kontinyu kalawan pangobatan sapertos gabapentin, pregabalin, atawa antidepressants tangtu, babarengan jeung agén topikal kawas lidocaine atawa capsaicin. Vaksinasi ngalawan virus varicella zoster disarankeun pikeun jalma dewasa umur 50 taun ka luhur pikeun ngirangan résiko shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Herpes zoster condong lumangsung leuwih sering dina jalma umur 50 taun ka luhur, utamana nu boga sistem imun lemah atawa nu ngagunakeun pangobatan imunosupresan. Éta dipicu ku aktivasi deui virus varicella‑zoster, virus anu sarua nu nyababkeun cacar. Gejala sapertos mual, nyeri, jeung gatel biasana muncul saméméh ruam khas. Komplikasi anu paling umum nyaéta neuralgia post‑herpetic, nyaéta nyeri saraf nu terus-terusan sanggeus ruamna ngaleungit. Faktor résiko jeung komplikasi anu patali jeung herpes zoster béda-béda gumantung kana umur, kaayaan imun, jeung waktos ngamimitian perlakuan. Vaksinasi pikeun individu umur 60 taun ka luhur geus kabuktian sacara signifikan ngirangan kajadian herpes zoster jeung neuralgia post‑herpetic. Ngamimitian pangobatan antiviral jeung pangurangan nyeri dina 72 jam ti mimiti ruam tiasa ngirangan parahna jeung komplikasi herpes zoster jeung neuralgia post‑herpetic.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Uji klinis sateuacan persetujuan nunjukkeun yén vaksin zoster hirup tiasa dianggo sakitar 50 dugi ka 70 %, sedengkeun vaksin rekombinan langkung saé, mimitian ti 90 dugi ka 97 %. Dina panilitian dunya nyata, hasilna ngadukung panemuan uji coba, nunjukkeun yén vaksin hirup sakitar 46 % efektif, sedengkeun vaksin rekombinan sakitar 85 %.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
Cacar, disebut ogé varicella, hasil tina inféksi awal ku virus, ilaharna lumangsung salila budak leutik atawa rumaja. Sakali cacar geus cageur, virus bisa tetep teu aktif (dormant) dina sél saraf manusa salila sababaraha taun atawa dekade, teras bisa diaktipkeun deui. Herpes zoster muncul nalika virus varicella anu dormant diaktipkeun deui. Virus teras ngalangkung sapanjang saraf ka kulit, ngahasilkeun bisul. Dina mangsa wabah herpes zoster, paparan ka virus varicella anu kapanggih dina lepuh herpes zoster bisa ngabalukarkeun cacar dina jalma nu teu acan ngalaman cacar.
Faktor résiko pikeun aktivasina deui virus dormant kalebet umur sepuh, fungsi imun anu goréng, jeung riwayat cacar saméméh umur 18 bulan. Virus varicella‑zoster henteu sami sareng virus herpes simplex, sanaos duanana kalebet kulawarga herpesvirus anu sami.
Vaksin herpes zoster ngurangan résiko herpes zoster ku 50 % nepi ka 90 %. Éta ogé ngirangan tingkat postherpetic neuralgia, sarta upami herpes zoster kajadian, ngirangan parahna. Upami herpes zoster berkembang, pangobatan antiviral sapertos aciclovir tiasa ngirangan parah jeung durasi panyakit upami dimimitian dina 72 jam sanggeus munculna ruam.
○ Perlakuan
Lamun lesi sumebar gancang, tingali dokter anjeun pas mungkin pikeun pangobatan antiviral. Duanana ubar antiviral jeung pangobatan neuralgia diperlukeun. Anjeun kedah istirahat sarta ngeureunkeun nginum alkohol.
#Acyclovir
#Fancyclovir
#Valacyclovir
#Gabapentin
#Pregabalin