Herpes zoster
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Herpes zoster bisul dina beuheung jeung taktak
References
Shingles, disababkeun ku réaktivasi virus varicella zoster anu tanggung jawab pikeun cacar, mangaruhan sakitar 1 juta jalma unggal taun di Amérika Serikat, kalayan résiko hirupna 30%. Jalma anu ngagaduhan sistem imun anu lemah sacara signifikan langkung rentan ka ngembangkeun shingles, kalayan gejala biasana dimimitian ku malaise, nyeri sirah, sareng muriang hampang, dituturkeun ku sensasi kulit anu teu biasa sababaraha dinten sateuacan munculna ruam. Baruntus ieu, biasana muncul dina wewengkon husus awak, progresses ti lepuh jelas ka sores crusted leuwih saminggu nepi ka sapuluh poé. Pangobatan anu gancang kalayan pangobatan antiviral (acyclovir, valacyclovir, or famciclovir) dina 72 jam saatos awal ruam penting pisan. Neuralgia postherpetic, komplikasi umum dicirikeun ku nyeri berkepanjangan di wewengkon nu dimaksud, mangaruhan ngeunaan hiji di lima penderita sarta merlukeun manajemén lumangsung kalawan pangobatan kayaning gabapentin, pregabalin, atawa antidepressants tangtu, babarengan jeung agén topical kawas lidocaine atanapi capsaicin. Vaksinasi ngalawan virus varicella zoster disarankeun pikeun sawawa yuswa 50 taun ka luhur pikeun ngirangan résiko shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Herpes zoster condong lumangsung leuwih remen di jalma yuswa 50 sarta heubeul, maranéhanana jeung sistim imun lemah, sarta maranéhanana nyokot pangobatan immunosuppressant. Éta dipicu ku aktivasina deui virus varicella-zoster, virus anu sami anu nyababkeun cacar. Gejala sapertos muriang, nyeri, sareng gatal-gatal biasana sateuacan munculna ruam anu khas. Komplikasi anu paling umum nyaéta neuralgia post-herpetic, nyaéta nyeri saraf anu terus-terusan saatos ruamna ngaleungitkeun. Faktor résiko sareng komplikasi anu aya hubunganana sareng herpes zoster béda-béda gumantung kana umur, kaséhatan imun, sareng waktos ngamimitian perlakuan. Vaksinasi pikeun individu anu umurna 60 taun ka luhur parantos kabuktian sacara signifikan ngirangan kajadian herpes zoster sareng neuralgia post-herpetic. Ngamimitian pangobatan antiviral sareng panawar nyeri dina 72 jam tina awal ruam tiasa ngirangan parah sareng komplikasi herpes zoster sareng neuralgia post-herpetic.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Uji klinis sateuacan persetujuan nunjukkeun yén vaksin zoster hirup tiasa dianggo sakitar 50 dugi ka 70%, sedengkeun vaksin rekombinan langkung saé, mimitian ti 90 dugi ka 97%. Dina panilitian dunya nyata, aranjeunna ngadukung panemuan uji coba, nunjukkeun yén vaksin hirup sakitar 46% efektif, sedengkeun anu rékombinan sakitar 85%.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
Cacar, disebut oge varicella, hasil tina inféksi awal jeung virus, ilaharna lumangsung salila budak leutik atawa rumaja. Sakali cacar cacar geus cageur, virus bisa tetep teu aktif (dormant) dina sél saraf manusa salila sababaraha taun atawa dekade, sanggeus éta bisa reactivated. Herpes zoster hasil nalika virus varicella dormant diaktipkeun deui. Lajeng virus ngarambat sapanjang awak saraf ka tungtung saraf dina kulit, ngahasilkeun bisul. Dina mangsa wabah herpes zoster , paparan ka virus varicella nu kapanggih dina lepuh herpes zoster bisa ngabalukarkeun cacar dina jalma nu teu acan ngalaman cacar.
Faktor résiko pikeun aktivasina deui virus dormant kalebet umur sepuh, fungsi imun anu goréng, sareng kaserang cacar sateuacan umur 18 bulan. Virus Varicella zoster henteu sami sareng virus herpes simpléks, sanaos duanana kalebet kulawarga herpesvirus anu sami.
Vaksin herpes zoster ngurangan résiko herpes zoster ku 50% nepi ka 90%. Éta ogé ngirangan tingkat neuralgia postherpetic, sareng, upami herpes zoster kajantenan, parahna. Upami herpes zoster berkembang, pangobatan antiviral sapertos aciclovir tiasa ngirangan parah sareng durasi panyakit upami dimimitian dina 72 jam saatos munculna ruam.
○ Perlakuan
Lamun lesions nyebarkeun gancang, tingali dokter Anjeun pas mungkin pikeun perlakuan antiviral.
Duanana ubar antiviral sareng pangobatan neuralgia diperyogikeun. Anjeun kedah istirahat sareng ngeureunkeun nginum alkohol.
#Acyclovir
#Fancyclovir
#Valacyclovir
#Gabapentin
#Pregabalin